Virion orientation in cubic crystals of the human common cold virus HRV14 |
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| Authors: | E Arnold J W Erickson G S Fout E A Frankenberger H J Hecht M Luo M G Rossman R R Rueckert |
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| Institution: | 1. Department of Biological Sciences, Purdue University W. Lafayette, Ind. 47907, U.S.A.;2. Biophysics Lab and Department of Biochemistry University of Wisconsin, Madison, Wis. 53706, U.S.A. |
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| Abstract: | A new cubic crystal form (a = 445.1 A) of space group P23 is reported for human rhinovirus R14. There are four particles per unit cell, each situated on a crystallographic 3-fold axis. The orientation of these particles has been determined with a rotation function and their approximate positions have been derived from a Patterson map. The crystals diffract to at least 2.8 A resolution. Limitations to the possible surface features of the virus are set by a comparison of the cubic and orthorhombic crystal forms. |
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| Keywords: | To whom correspondence should be adressed |
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