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A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer

Authors:	Kai-Hsiung Chang,Rui Li,Barbara Kuri,Yair Lotan,Claus G. Roehrborn,Jiayan Liu,Robert Vessella,Peter S. Nelson,Payal Kapur,Xiaofeng Guo,Hamid Mirzaei,Richard J. Auchus,Nima Sharifi

Affiliation:	¹ Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA;² Department of Solid Tumor Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH 44195, USA;³ Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, OH 44195, USA;⁴ Division of Hematology/Oncology, Department of Internal Medicine and Simmons Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA;⁵ Department of Urology, UT Southwestern Medical Center, Dallas, TX 75390, USA;⁶ Department of Pathology, UT Southwestern Medical Center, Dallas, TX 75390, USA;⁷ Department of Biochemistry, UT Southwestern Medical Center, Dallas, TX 75390, USA;⁸ Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA;⁹ Department of Urology, University of Washington School of Medicine, Seattle, WA 91809, USA;¹⁰ Divisions of Human Biology and Clinical Research, Fred Hutchinson Cancer Research Center, Seattle, WA 91809, USA

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