A mini review on the antimicrobial peptides isolated from the genus <Emphasis Type="Italic">Hylarana</Emphasis> (Amphibia: Anura) with a proposed nomenclature for amphibian skin peptides |
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Authors: | Priya?Thomas T?V?Vineeth Kumar V?Reshmy K?S?Kumar Email author" target="_blank">S?GeorgeEmail author |
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Institution: | (1) Chemical Biology Group, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, 695014, Kerala, India; |
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Abstract: | Hylarana is a well established frog genus coming under the family Ranidae. An increasing number of antimicrobial peptides have been
isolated and characterized from the skin of frogs of this genus. This review covers the antimicrobial peptides reported so
far from the frogs of Hylarana genus and to propose a consistent system of nomenclature for amphibian skin peptides. Multiple sequence alignment of the
skin peptides from Hylarana genus has grouped them into six peptide families, and three bioactive peptides. Existing nomenclature of amphibian antimicrobial
peptides is species centered with no implication to the genus which can lead to disparities, when frogs with same species
name belonging to different genus have to be named. As per the proposed system the peptide should have the parent peptide
name (e.g. Brevinin-1) followed by two uppercase letter of the genus, if two genera begin with the same letter–first letter
should be the same followed by an appropriate second letter (e.g. HU for Huia and HM for Humenerana). This is succeeded by species name in lower case-orthologous peptides from different species may be characterized by the
initial letter of that species, when two species begin with the same initial letter, second letter should be used appropriately
(e.g. HLat for Hylarana aurata and HLan for Hylarana aurantiaca). Paralogs belonging to the same peptide family are assigned by numbers. |
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