Genetic and cell biological aspects of the yeast vacuolar H+-ATPase |
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| Authors: | Yasuhiro Anraku Naoyuki Umemoto Ryogo Hirata Yoshikazu Ohya |
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| Affiliation: | (1) Department of Biology, Faculty of Science, University of Tokyo, Hongo, Bunkyo-ku, 113 Tokyo, Japan |
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| Abstract: | The yeast vacuolar proton-translocating ATPase is a member of the third class of H+-pumping ATPase. A family of this type of H+-ATPase is now known to be ubiquitously distributed in eukaryotic vacuo-lysosomal organelles and archaebacteria. NineVMA genes that are indispensable for expression of the enzyme activity have been cloned and characterized in the yeastSaccharomyces cerevisiae. This review summarizes currently available information on theVMA genes and cell biological functions of theVMA gene products. |
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| Keywords: | Vacuolar H+-ATPase VMA genes Saccharomyces cerevisiae |
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