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Stable SREBP-1a knockdown decreases the cell proliferation rate in human preadipocyte cells without inducing senescence |
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| Authors: | María Soledad Alvarez Ana Fernandez-Alvarez Carme Cucarella Marta Casado |
| Institution: | 1. Instituto de Biomedicina de Valencia (IBV-CSIC), Jaime Roig 11, E-46010 Valencia, Spain;2. Fundación Instituto Leloir, IIBBA-CONICET, Av. Patricias Argentinas 435, Ciudad Autónoma de Buenos Aires C1405BWE, Argentina |
| Abstract: | |
| Keywords: | CDKN1A cyclin-dependent kinase inhibitor 1A CDKN2B cyclin-dependent kinase inhibitor 2B CDKN3 cyclin-dependent kinase inhibitor 3 H3K9me3 histone H3 lysine 9 trimethylation MTT 3-(4 5-dimethyl-thiazol-2-yl)-2 5-diphenyltetrazolium bromide RRBP8 retinoblastoma binding protein 8 SA-β-Gal senescence-associated β-galactosidase SGBS Simpson-Golabi Behmel Syndrome shRNA short hairpin RNA SREBP sterol regulatory element binding protein |
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