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Engineering of electron transfer properties of metallo-proteins
Authors:Gerard W. Canters  Gertie van Pouderoyen
Affiliation:

Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, PO Box 9502, 2300 RA Leiden, The Netherlands

Abstract:The results of site-directed mutagenesis experiments on azurins and cytochrome c-550, aimed at modifying the redox properties of the metal centres, are presented and discussed. Applications in the design of bioelectronic devices are briefly discussed.
Keywords:biosensor   electron transfer   metalloproteins   redoxchemistry   blue copper   cytochrome   copper protein
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