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New Strategies of LIBS-Based Validation of Glycemic Elements for Diabetes Management |
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| Authors: | Prashant Kumar Rai Dolly Jaiswal Nilesh K Rai Shiwani Pandhija A K Rai Geeta Watal |
| Institution: | (1) Alternative Therapeutics Unit, Drug Discovery & Development Division, Medicinal Research Lab, Department of Chemistry, University of Allahabad, Allahabad, 211002, India;(2) Laser Spectroscopy Research Laboratory, Department of Physics, University of Allahabad, Allahabad, 211002, India; |
| Abstract: | Antidiabetic efficacy of medicinal plant cannot be ignored in order to develop drugs without toxicity and side effects. Trace elements present in plant material is responsible for their medicinal nature and hence it is necessary to know the major and minor constituents of the plant material. Laser-induced breakdown spectroscopy (LIBS) is a very efficient and powerful analytical tool to monitor the elements present in sample. The present study deals with the LIBS-based validation of glycemic elements present in Withania coagulans and Cajanus cajan medicinal herbs. The decreasing blood glucose level and improving glucose tolerance test significantly showed that the higher content of Mg and Ca in W. coagulans in comparison to C. cajan is responsible for its significant role in diabetes management, whereas the concentration of other elements are nearly the same in both extracts. |
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