| 间歇性外斜视患儿的注意跟踪能力异常 |
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| 引用本文： | 周丽琴,左真涛,王静,傅涛,陈霖.间歇性外斜视患儿的注意跟踪能力异常[J].生物化学与生物物理进展,2017,44(5):407-413. |
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| 作者姓名： | 周丽琴 左真涛 王静 傅涛 陈霖 |
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| 作者单位： | 中国科学院生物物理研究所，脑与认知科学国家重点实验室，北京 100101；中国科学院大学，北京100049,中国科学院生物物理研究所，脑与认知科学国家重点实验室，北京 100101,首都医科大学附属北京同仁医院，北京同仁眼科中心，北京市眼科学与视觉科学重点实验室，北京100730,首都医科大学附属北京同仁医院，北京同仁眼科中心，北京市眼科学与视觉科学重点实验室，北京100730,中国科学院生物物理研究所，脑与认知科学国家重点实验室，北京 100101；中国科学院大学，北京100049；中国科学院脑科学卓越创新中心，上海 200031 |
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| 基金项目： | 国家重点基础研究发展计划(973)(2012CB825500, 2015CB351701),国家自然科学基金(91132302)和中国科学院基金(XDB02010001, XDB02050001)资助项目 |
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| 摘 要： | 间歇性外斜视是儿童眼科的常见疾病之一,也是目前眼科学研究的热点领域之一.本研究使用多物体跟踪实验范式,系统考察了间歇性外斜视儿童,相对于弱视儿童以及正常对照儿童,注意的容量是否存在异常.实验结果发现间歇性外斜视儿童和弱视儿童的注意跟踪能力都显著地差于正常对照儿童,而且间歇性外斜视儿童和弱视儿童的跟踪成绩基本没有差别,他们的注意跟踪功能的受损程度相近.本研究首次报道了间歇性外斜视儿童注意能力的行为异常,对进一步研究间歇性外斜视的发病机理和早期临床诊断具有潜在的参考意义.
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| 关 键 词： | 间歇性外斜视，弱视，注意跟踪，运动 |
| 收稿时间： | 2017/3/20 0:00:00 |
| 修稿时间： | 2017/4/12 0:00:00 |
Abnormal Attentive Tracking in Children With Intermittent Exotropia |
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| ZHOU Li-Qin,ZUO Zhen-Tao,WANG Jing,FU Tao and CHEN Lin.Abnormal Attentive Tracking in Children With Intermittent Exotropia[J].Progress In Biochemistry and Biophysics,2017,44(5):407-413. |
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| Authors: | ZHOU Li-Qin ZUO Zhen-Tao WANG Jing FU Tao and CHEN Lin |
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| Institution: | Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China,Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China,Beijing Tongren Eye Centre, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing 100730, China,Beijing Tongren Eye Centre, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing 100730, China and Key Laboratory of Brain and Cognitive Science, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China; The Innovation Center of Excellence on Brain Science, Chinese Academy of Sciences, Shanghai 200031, China |
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| Abstract: | Intermittent exotropia is a common pediatric ocular disease, which is also a hot research area in ophthalmology. In this study, we tested the tracking ability of children with intermittent exotropia using multiple object tracking (MOT) paradigm, and compared with amblyopic children and normal children. The experimental results showed that the tracking capacity of children whether with intermittent exotropia or amblyopia was significantly decreased as compared with normal children, and children with intermittent exotropia suffers the same degree of damage with children with amblyopia. It is the first report of the abnormal attentive ability of children with intermittent exotropia, which may be beneficial to future research of pathogenesis and early diagnosis of the disease. |
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| Keywords: | intermittent exotropia amblyopia attentive tracking motion |
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