吐鲁番市胃食管反流病发生相关危险因素分析（附280例报道）

目的：探讨280例胃食管反流病（GERD）的分布特点及危险因素。方法：对临床诊断和胃镜确诊的280例GERD患者进行临床和风险因子相关性分析。结果：不论汉族还是维族，男性患者比例均明显高于女性；汉族患者高发年龄段早于维族患者（z=-2．939，P=0．003，）；汉族和维族患者占反流性食管炎和Barrett食管比例分别为42．4％、81_3％及56．5％、18．8％，其中汉族患者Barrett食管比例较高（X2=14．358，P=0．000）；肥胖、习惯性便秘、重体力活动者、饮食习惯不良在维族患者中的比例较高（P〈0．001）。结论：GERD与性别、年龄密切相关，男性多于女性，汉族患者发病年龄高峰旱于维族患者；汉族患者Barrett食管发生比例高于维族患者；肥胖、习惯性便秘、重体力活动、饮食习惯不良可能是GERD尤其是维族人群GERD的危险因素。

Analysis of Gastroesophageal Reflux Disease Associated Risk Factors in City of Turpan （ 280 cases report）

Objective： Distribution and risk factors of 280 gastroesophageal reflux disease （GERD）in City of Turpan were discu- ssed. Methods： Definite diagnosis for 280 patients suffered from GERD was made by clinical diagnosis and gastroscope, and further relation to risk factors was analysized. Results： In both Han nationality Group and Uygur ethnic group, the number of male patients was significantly higher than famale patients; Han nationality patients were significantly younger than Uygur ethnic patients （Z= -2.939, P=0. 003 ）; rate of reflux esophagitis and Barrett esophagus was respectively 42.4%, 81.3% in Han nationality group and 56.5%, 18.8% in Uygur ethnic group, and rate of Barrett esophagus was higher in Han nationality group than in Uygur ethnic group（X2=14.358, P=0.000）; Rates of patients with adiposity, habitual constipation, Heavy physical activity, bad eating habits were higher in Uygur ethnic group than in Han nationality group （P〈0.001）. Conclusion： GERD was closely associated with gender and age, and male patients were more than famale patients, Han nationality patients were significantly younger than Uygur ethnic patients, ate of Barrett esophagus was higher in Han nationality group than in Uygur ethnic group; adiposity, habitual constipation, Heavy physical activity, bad eating habits were risk factors for GERD, especially for Uygur ethnic group.