苦槛蓝叶的黄酮类成分及其荔枝霜疫霉抑制活性研究

为了解苦槛蓝(Myoporum bontioides)的化学成分，采用色谱分离法从叶中分离得到11个化合物，分别鉴定为：5, 7, 3?-三羟基-4?-甲氧基黄酮(1)、3, 5, 7, 4?-四羟基-3?-甲氧基黄酮(2)、5, 7, 4?-三羟基-3?, 5?-二甲氧基黄酮(3)、木犀草素(4)、山奈酚(5)、鼠李黄素(6)、5, 7-二羟基二氢黄酮(7)、7, 4?-二羟基二氢黄酮(8)、5, 7, 3?, 4?-四羟基二氢黄酮(9)、5-O-乙酰基-3, 7, 3?, 4?-四羟基二氢黄酮(10)和7-甲氧基香橙素(11)。除化合物4、7、11之外，其他化合物均为首次从苦槛蓝叶中分离得到。菌丝生长速率法测试表明化合物4、7~9和11对荔枝霜疫霉菌具有较好的抑菌活性。

Flavonoids from Leaves of Myoporum bontioides and Their Antimicrobial Activities against Peronophythora litchi

In order to study the chemical compositions in Myoporum bontioides, eleven compounds were isolated from leaves by chromatographic separation methods. On the basis of spectral data, they were identified as 5, 7, 3?-trishydroxy-4?-methoxyflavone (1), 3, 5, 7, 4?-tetrahydroxy-3?-methoxyflavone (2), 5, 7, 4?-trihydroxy-3?, 5?-dimethoxyflavone (3), 3'', 4'', 5, 7-tetrahydroxyflavanone (4), kaempferol (5), rhamnetin (6), 5, 7-dihydroxyfla-vanone (7), 7, 4''-dihydroxyflavanone (8), 5, 7, 3?, 4?-trihydroxyflavanone (9) 5-acetyloxy-3, 7, 3?, 4?-tetrahydroxy- flavanone (10) and 7-methoxyaromadenrin (11). All compounds were obtained from M. bontioides for the first time except compounds4,7 and11. The compounds4,7-9 and11 had strong antifungal activity against Peronophythora litchi.