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Favin, a crystalline lectin from Vicia faba
Authors:J L Wang  J W Becker  G M Edelman  G N Reeke
Affiliation:The Rockefeller University New York, N.Y. 10021, U.S.A.
Abstract:A lectin from the fava bean (Vicia faba) has been purified and crystallized in a form suitable for high-resolution crystallographic structure analysis. This protein binds glucose- and mannose-like saccharides, and it is mitogenic for lymphocytes. The fava lectin crystallizes in the orthorhombic space group. P212121 with unit cell dimensions a = 90.0, b = 89.3, and c = 67.4 A?. The mass of protein in the asymmetric unit is 53,000 daltons, corresponding to the molecular weight of the protein in solution.
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