| 以核多角体病毒为载体在家蚕中生产外源蛋白 |
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| 引用本文： | 张雨青.以核多角体病毒为载体在家蚕中生产外源蛋白[J].生物化学与生物物理进展,1994,21(5):406-410. |
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| 作者姓名： | 张雨青 |
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| 作者单位： | 苏州蚕桑专科学校 |
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| 摘 要： | 以家蚕核多角体病毒(BmNPV)为载体,在家蚕幼虫或家蚕培养细胞系中表达的外源基因越来越多,其表达的产物已涉及到医用药物、医疗诊断、疫苗生产、生物防治等诸多领域,文章就BmNPV的特性及其基因组构造,多角体蛋白基因的特性,重组BmNPV的构建及其在家蚕幼虫体内和细胞系中的表达,BmNPV-家蚕表达系统的外源蛋白生产效率及其应用等各个方面作了全面、系统的综述.
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| 关 键 词： | 家蚕 家蚕核多角体病毒 多角体蛋白基因 基因表达 重组病毒 表达载体 |
| 收稿时间： | 1993/9/16 0:00:00 |
| 修稿时间： | 1993/11/17 0:00:00 |
Production of the Useful Protein in the Silkworm Using the Bombyx mori Nuclear Polyhedrosis Virus as a Expression Vector |
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| Zhang Yuqing.Production of the Useful Protein in the Silkworm Using the Bombyx mori Nuclear Polyhedrosis Virus as a Expression Vector[J].Progress In Biochemistry and Biophysics,1994,21(5):406-410. |
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| Authors: | Zhang Yuqing |
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| Institution: | Suzhou Sericulture College |
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| Abstract: | More and more foreign genes have been expressed in the silkworm larvae or silkworm cell lines using the Bombyx mori nuclear polyhedrosis virus (BmNPV) as a expression vector.The expressed products involve in many fields such as pharmaceutics, medical diagnosis, vaccine production and biological control. The characteristics of BmNPV and its genome structure,characteristics of polyhedrin gene,construction of recombinant BmNPV and its expression in the silkworm larvae and cell line, and efficiency of production for the foreign gene products expressed in the silkworm-BmNPV system and application of the expressed product were described systematically in the review. |
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| Keywords: | silkworm Bonibyx mori nuclear polyhedrosis virus polyhedrin gene gene expression recombinant virus expression vector |
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