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Antimutagenic activity of soybeans fermented with basidiomycetes in Ames/Salmonella test |
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| Authors: | So-Yeun Kim Yun-Hee Shon Jae-Sung Lee Cheorl-Ho Kim Kyung-Soo Nam |
| Affiliation: | (1) Department of Food Science and Technology, Yeungnam University, Kyongsan , 712-749, Korea;(2) Department of Pharmacology, College of Medicine and Intractable Disease Research Center, Dongguk University, Kyongju , 780-714, Korea;(3) Department of Biochemistry, College of Oriental Medicine, Dongguk University, Kyongju , 780-714, Korea |
| Abstract: | Soybeans fermented with either Phellinus igniarius or Agrocybe cylindracea inhibited the mutagenicity of the directly-acting mutagens: 4-nitro-o-phenylenediamine on Salmonella typhimurium strain TA 98 and NaN3 on S. typhimurium strain TA 100; and indirectly-acting mutagens, 2-aminofluorene using strain TA 98 and benzo[a]pyrene using strain TA 100, in the presence of a supernatant solution from mammalian hepatic microsomes. |
| Keywords: | Agrocybe cylindracea antimutagenicity Phellinus igniarius soybeans |
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