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Antimutagenic activity of soybeans fermented with basidiomycetes in Ames/Salmonella test
Authors:So-Yeun Kim  Yun-Hee Shon  Jae-Sung Lee  Cheorl-Ho Kim  Kyung-Soo Nam
Institution:(1) Department of Food Science and Technology, Yeungnam University, Kyongsan , 712-749, Korea;(2) Department of Pharmacology, College of Medicine and Intractable Disease Research Center, Dongguk University, Kyongju , 780-714, Korea;(3) Department of Biochemistry, College of Oriental Medicine, Dongguk University, Kyongju , 780-714, Korea
Abstract:Soybeans fermented with either Phellinus igniarius or Agrocybe cylindracea inhibited the mutagenicity of the directly-acting mutagens: 4-nitro-o-phenylenediamine on Salmonella typhimurium strain TA 98 and NaN3 on S. typhimurium strain TA 100; and indirectly-acting mutagens, 2-aminofluorene using strain TA 98 and benzoa]pyrene using strain TA 100, in the presence of a supernatant solution from mammalian hepatic microsomes.
Keywords:Agrocybe cylindracea  antimutagenicity  Phellinus igniarius  soybeans
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