A novel polypeptide from Cervus nippon Temminck proliferation of epidermal cells and NIH3T3 cell line |
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| Authors: | Guan Shu-Wen Duan Leng-Xin Li Yuan-Yuan Wang Ben-Xiang Zhou Qiu-Li |
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| Affiliation: | Laboratory of Biological Macromolecule, College of Life Science, Changchun, China. |
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| Abstract: | ![]()
A novel polypeptide, velvet antler polypeptide (VAPPs), having a stimulary effect on proliferation of some cell was isolated from the velvet antler of sika deer (Cervus nippon Temminck). This polypeptide consists of a single chain of 32 amino-acid residues VLSAT DKTNV LAAWG KVGGN APAFG AEALE RM. VAPPs showed marked stimulary effect on rat epidermal cells and NIH3T3 cell line (dose range from 10-40 mg x L(-1) and 5-80 mg x L(-1), respectively). |
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