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Whole-Genome Sequence of Livestock-Associated ST398 Methicillin-Resistant Staphylococcus aureus Isolated from Humans in Canada
Authors:George R. Golding  Louis Bryden  Paul N. Levett  Ryan R. McDonald  Alice Wong  Morag R. Graham  Shaun Tyler  Gary Van Domselaar  Philip Mabon  Heather Kent  Patrick Butaye  Tara C. Smith  Kristina Kadlec  Stefan Schwarz  Scott J. Weese  Michael R. Mulvey
Abstract:
Despite reports of high colonization rates of ST398 livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) among pigs and pig farmers, the incidence of LA-MRSA infection in the general population in Canada appears to be rare in comparison to that in some European countries. In this study, the complete genome sequence of a Canadian representative LA-MRSA isolate (08BA02176) from a human postoperative surgical site infection was acquired and compared to the sequenced genome of an LA-MRSA isolate (S0385) from Europe to identify genetic traits that may explain differences in the success of these particular strains in some locales.
Keywords:
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