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葛根抗腹泻药效组分实验研究
引用本文:黄伟强,金哲雄,张贵君,刘娜,文春先.葛根抗腹泻药效组分实验研究[J].现代生物医学进展,2010,10(1).
作者姓名:黄伟强  金哲雄  张贵君  刘娜  文春先
作者单位:1. 北京中医药大学中药学院,北京,100102;哈尔滨商业大学药学院,黑龙江,哈尔滨,150076
2. 哈尔滨商业大学药学院,黑龙江,哈尔滨,150076
3. 北京中医药大学中药学院,北京,100102
摘    要:目的:验证葛根抗腹泻的药效组分,为葛根的质量评价提供科学数据。方法:在经方葛根芩连汤的基础上分析葛根抗腹泻的药效组分,采用组合药理实验辅助验证药效组分。结果:抗腹泻相关实验中葛根水煎液中、高剂量组、葛根药效组分组、葛根芩连汤组与阴性对照组比较均有显著性差异(P0.01)。结论:葛根素-大豆苷-大豆苷元-3'-羟基葛根素是葛根抗腹泻的药效组分。

关 键 词:葛根  抗腹泻  药效组分  质量评价  葛根芩连汤  

Study on Active Components Alignment of Anti-diarrhea in Radix Puerariae
HUANG Wei-qiang,JIN Zhe-xiong,ZHANG Gui-jun,LIU Na,MUN Chun-sun.Study on Active Components Alignment of Anti-diarrhea in Radix Puerariae[J].Progress in Modern Biomedicine,2010,10(1).
Authors:HUANG Wei-qiang  JIN Zhe-xiong  ZHANG Gui-jun  LIU Na  MUN Chun-sun
Institution:HUANG Wei-qiang1,2,JIN Zhe-xiong2,ZHANG Gui-jun1,LIU Na1,MUN Chun-sun1(1 College of Pharmacy,Beijing University of Chinese Medicine,Beijing 100102,China,2 College of Pharmacy,Harbin University of Commerce,Harbin150076,China)
Abstract:Objective:To verify the active components alignment of anti-diarrhea and provide scientific data for the quality evaluation on Radix Puerariae.Methods:To analyze the active components alignment of Radix Puerariae anti-diarrhea on the base of Gengen Qinlian Decoction.Combination pharmacological experiment was used to verify the active components alignment.Result:In the relevant experiments of anti-diarrhea,comparing with the control group,there was significant difference among the medium-dose group and the h...
Keywords:Radix Puerariae  Anti-diarrhea  Active components alignment  Quality evaluation  Gengen Qinlian Decoction  
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