儿童副流感病毒、肺炎支原体感染情况研究

摘要 目的：通过检测及分析住院患儿血清中副流感病毒、肺炎支原体IgM抗体，探讨两种病原体感染的流行病学特征。方法：应用酶联免疫分析的方法定性检测患儿血清中的副流感病毒、肺炎支原体IgM抗体，采用卡方检验对不同年份、性别、年龄及季节的数据进行分析。结果：副流感病毒、肺炎支原体阳性率分别为3.6%、22.4%，混合感染的阳性率为1.3%。PIV每年女性患儿比男性患儿阳性率高，每一年中6-14岁感染阳性率最高；MP每年女性患儿比男性患儿阳性率高，随着年龄增长感染的阳性率也升高，6-14岁阳性率最高。PIV与MP在每年的四季中，感染的阳性率各不相同，并且没有相对的规律可循，但是在冬季阳性率还是较高，其次是春季、秋季，最低的是夏季。结论：掌握儿童副流感病毒和肺炎支原体感染流行病学特点，有助于了解疾病感染特点，从而在疾病的不同时期及时快速地采取相应措施。

Study on the Infection of Parainfluenza Virus and Mycoplasma Pneumoniae in Children

ABSTRACT Objective: To investigate the epidemiological characteristics of infections by the two pathogens by detecting and analyzing the IgM antibodies of parainfluenza virus and Mycoplasma pneumoniae in the sera of hospitalized children. Methods: The serum IgM antibodies of parainfluenza virus and mycoplasma pneumoniae were detected by elisa, and the data of different years, genders, ages and seasons were analyzed by Chi-square test. Results: The positive rates of parainfluenza virus and Mycoplasma pneumoniae were 3.6% and 22.4%, respectively, and the positive rate of mixed infection was 1.3%. The annual positive rate of female children with PIV is higher than that of male children, and the positive rate of infection is highest in 6-14 year olds every year; the positive rate of female children with MP is higher than that of male children every year, and the positive rate of infection increases with age, The highest positive rate is 6-14 years old.PIV and MP have different positive rates of infection in the four seasons of each year, and there is no relative rule to follow. However, the positive rate is still higher in winter, followed by spring and autumn, and the lowest is summer. Conclusion: Mastering the epidemiological characteristics of parainfluenza virus and Mycoplasma pneumoniae infection in children will help to understand the characteristics of disease infection, so that corresponding measures can be taken promptly and quickly in different periods of the disease.