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糖化血红蛋白与糖尿病及其并发症的关系
引用本文:李之珍胡晓武许霞杨飞孙晓祥.糖化血红蛋白与糖尿病及其并发症的关系[J].现代生物医学进展,2011,11(21):4123-4125.
作者姓名:李之珍胡晓武许霞杨飞孙晓祥
作者单位:东南大学医学院附属医院马鞍山市立医疗集团临床检验中心 安徽马鞍山243000
摘    要:目的:探讨糖化血红蛋白(HbAlc)与糖尿病诊断、疗效评价及并发症的关系。方法:选择2型糖尿病患者250例和健康体检者150例,分别测定空腹血糖(FPG)、2h血糖(2hPG)及糖化血红蛋白(HbA1c),统计学分析HbA1c与FPG、2hPG的相关性;分析HbA1c与糖尿病并发症发生的关系。结果:糖尿病组FPG、2hPG及HbA1c水平均显著高于对照组(P<0.01);糖尿病伴有并发症患者的HbAlc明显高于无并发症者(P<0.05),HbA1c水平与糖尿病并发症的发生率存在高度相关性(P<0.01)。结论:检测外周血中HbA1c水平对2型糖尿病诊断、疗效评价具有重要临床价值,控制糖化血红蛋白对预防糖尿病并发症的发生具有重要意义。

关 键 词:糖化血红蛋白  糖尿病  空腹血糖  餐后2h血糖

The Value of Glycosylated Hemoglobin 1c Detection in Diagnosis and Complications of Diabetes in Diabetes
LI Zhi-zhen,HU Xiao-wu,XU Xi,YANG Fei,SUN Xiao-xiang.The Value of Glycosylated Hemoglobin 1c Detection in Diagnosis and Complications of Diabetes in Diabetes[J].Progress in Modern Biomedicine,2011,11(21):4123-4125.
Authors:LI Zhi-zhen  HU Xiao-wu  XU Xi  YANG Fei  SUN Xiao-xiang
Institution:LI Zhi-zhen,HU Xiao-wu,XU Xia,YANG Fei,SUN Xiao-xiang (Clinical Laboratory Centre of Medical Group in Maanshan City,An-hui,Maanshan 243000)
Abstract:Objective: To investigate the Glycosylated hemoglobin1c(HbA1c) test for diagnosis of diabetes,efficacy evaluation and prediction of complications in clinical value.Methods: Choose patients with type 2 diabetes mellitus(T2DM group) 250 cases and healthy subjects(control group) 150 patients,measured by fasting plasma glucose(FPG),2 hour plasma glucose(2hPG) and glycated hemoglobin(HbA1c),then compared analysis of HbA1c and FPG,2hPG relationship,and analyzed the relationship between HbA1c and the diabetes rela...
Keywords:Glycated hemoglobin  Diabetes  Fasting plasma glucose  2 hour plasma glucose  
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