| Ghrelin 发现和结构的研究现状 |
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| 引用本文： | 王丽晔李峰,宋月晗马佳美李思耐关冰河.Ghrelin 发现和结构的研究现状[J].现代生物医学进展,2011,11(18):3589-3591. |
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| 作者姓名： | 王丽晔李峰 宋月晗马佳美李思耐关冰河 |
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| 作者单位： | 北京中医药大学 北京100029 |
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| 基金项目： | 北京中医药大学自主课题 |
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| 摘 要： | Ghrelin是生长激素促分泌素受体(growth hormone secretagogue receptor,GHSR)的内源性配体,是1999年由Kojima等]人从大鼠胃组织中发现的含28个氨基酸的多肽,主要由胃黏膜泌酸腺X/A样细胞分泌并通过与其特异性受体结合而产生多种生物学效应。本文总结了近几年的文章,旨在通过对Ghrelin的发现和结构的介绍,为以后的相关研究奠定基础。
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| 关 键 词： | Ghrelin 脑肠肽 结构 |
The discovery and structure of Ghrelin |
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| WANG Li-ye,LI Feng,SONG Yue-han,MA Jia-mei,LI Si-nai,Guan Bing-he.The discovery and structure of Ghrelin[J].Progress in Modern Biomedicine,2011,11(18):3589-3591. |
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| Authors: | WANG Li-ye LI Feng SONG Yue-han MA Jia-mei LI Si-nai Guan Bing-he |
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| Institution: | WANG Li-ye,LI Feng,SONG Yue-han,MA Jia-mei,LI Si-nai,Guan Bing-he(Beijing University of Chinese Medicine,100029,Beijing,China) |
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| Abstract: | Ghrelin is the endogenic ligand of growth hormone secretagogue receptor(GHSR),it was detected in stomach of mouse by Kojima in 1999 for the first time,it is a polypeptide which has 28 amino acids.Ghrelin is excreted by X/A cells in stomach mu-cous membrane secretory and do the deed through combing with its specificity antibody.The article summarizes many papers which ap-peard in recent years and wants to lay the foundation of correlational investigation. |
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| Keywords: | Ghrelin Braingut petide Structure |
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