Comparing unilateral and bilateral upper limb training: The ULTRA-stroke program design |
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| Authors: | A EQ van Delden C E Peper Jaap Harlaar Andreas Daffertshofer Nienke I Zijp Kirsten Nienhuys Peter Koppe Gert Kwakkel Peter J Beek |
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| Institution: | (1) Research Institute MOVE, Faculty of Human Movement Sciences, VU University Amsterdam, Van der Boechorststraat 9, 1081 BT Amsterdam, The Netherlands;(2) Department of Rehabilitation Medicine, Research Institute MOVE, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands;(3) Rehabilitation Centre Amsterdam, Overtoom 283, 1054 HW Amsterdam, The Netherlands |
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| Abstract: | Background About 80% of all stroke survivors have an upper limb paresis immediately after stroke, only about a third of whom (30 to 40%)
regain some dexterity within six months following conventional treatment programs. Of late, however, two recently developed
interventions - constraint-induced movement therapy (CIMT) and bilateral arm training with rhythmic auditory cueing (BATRAC)
- have shown promising results in the treatment of upper limb paresis in chronic stroke patients. The ULTRA-stroke (acronym
for Upper Limb TRaining After stroke) program was conceived to assess the effectiveness of these interventions in subacute
stroke patients and to examine how the observed changes in sensori-motor functioning relate to changes in stroke recovery
mechanisms associated with peripheral stiffness, interlimb interactions, and cortical inter- and intrahemispheric networks.
The present paper describes the design of this single-blinded randomized clinical trial (RCT), which has recently started
and will take several years to complete. |
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