Rooting the eutherian tree: the power and pitfalls of phylogenomics |
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| Authors: | Hidenori Nishihara Norihiro Okada Masami Hasegawa |
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| Affiliation: | (1) Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, 4259-B-21 Nagatsuta-cho, Midori-ku, 226-8501, Yokohama, Japan;(2) Department of Statistical Modeling, Institute of Statistical Mathematics, 4-6-7 Minami-Azabu, Minato-ku 106-8569, Tokyo, Japan;(3) School of Life Sciences, Fudan University, Handan Road 220#, Shanghai, 200433, China |
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| Abstract: | ![]()
Background Ongoing genome sequencing projects have led to a phylogenetic approach based on genome-scale data (phylogenomics), which is beginning to shed light on longstanding unresolved phylogenetic issues. The use of large datasets in phylogenomic analysis results in a global increase in resolution due to a decrease in sampling error. However, a fully resolved tree can still be wrong if the phylogenetic inference is biased. |
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