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Sequential disassembly of vertebrate muscle thick filaments
Authors:J. Trinick  J. Cooper
Affiliation:Agricultural Research Council Meat Research Institute Langford, Bristol BS18 7DY, England
Abstract:Native thick filaments from rabbit psoas muscle have been sequentially dissolved by incremental rises in salt concentration. Three quite separate stages of depolymerization can be detected; these presumably reflect constraints imposed on the disassembly process by variations in the packing of myosin and by the presence of other thick filament proteins.
Keywords:EGTA
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