Adipose-derived stem cells: Implications in tissue regeneration |
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| Authors: | Wakako Tsuji J Peter Rubin Kacey G Marra |
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| Institution: | Wakako Tsuji, J Peter Rubin, Kacey G Marra, Adipose Stem Cell Center, Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, PA 15213, United StatesJ Peter Rubin, Kacey G Marra, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, PA 15213, United StatesJ Peter Rubin, Kacey G Marra, Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15213, United States |
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| Abstract: | Adipose-derived stem cells (ASCs) are mesenchymal stem cells (MSCs) that are obtained from abundant adipose tissue, adherent on plastic culture flasks, can be expanded in vitro, and have the capacity to differentiate into multiple cell lineages. Unlike bone marrow-derived MSCs, ASCs can be obtained from abundant adipose tissue by a minimally invasive procedure, which results in a high number of cells. Therefore, ASCs are promising for regenerating tissues and organs damaged by injury and diseases. This article reviews the implications of ASCs in tissue regeneration. |
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| Keywords: | Mesenchymal stem cells Adipose-derived stem cells Differentiation Growth factors Tissue engineering Clinical trials |
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| 点击此处可从《World journal of stem cells》浏览原始摘要信息 |
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