5-Methylcytosine in heterochromatic regions of chromosomes in Bovidae |
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| Authors: | W. Schnedl B. F. Erlanger O. J. Miller |
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| Affiliation: | (1) Histologisch-Embryologisches Institut, University of Vienna, Vienna;(2) Department of Microbiology College of Physicians and Surgeons, Columbia University, Columbia;(3) Department of Human Genetics and Development College of Physicians and Surgeons, Columbia University, Columbia;(4) Department of Obstetrics and Gynecology, College of Physicians and Surgeons, Columbia University, Columbia |
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| Abstract: | Summary The centromeric regions of cattle, goat and sheep chromosomes bind anti-5-MeC as revealed by immunofluorescence technique, indicating concentration of 5-MeC at these heterochromatic regions. The centromere of the submetacentric X of cattle remains nearly unstained and so do the centromeres of the acrocentric X chromosomes in goat and sheep. The short arm of the cattle Y exhibits strong anti-5-MeC binding whereas the tiny Y chromosomes of goat and sheep contain no brightly fluorescent material. |
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