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Design considerations for efficient and effective microarray studies
Authors:Kerr M Kathleen
Institution:Department of Biostatistics, University of Washington, Box 357232, Seattle, Washington, USA. katiek@u.washington.edu
Abstract:This article describes the theoretical and practical issues in experimental design for gene expression microarrays. Specifically, this article 1) discusses the basic principles of design (randomization, replication, and blocking) as they pertain to microarrays, and 2) provides some general guidelines for statisticians designing microarray studies.
Keywords:Block design  Composite sampling  Experimental design  Gene expression  Microarray  Replication
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