Design considerations for efficient and effective microarray studies |
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Authors: | Kerr M Kathleen |
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Institution: | Department of Biostatistics, University of Washington, Box 357232, Seattle, Washington, USA. katiek@u.washington.edu |
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Abstract: | This article describes the theoretical and practical issues in experimental design for gene expression microarrays. Specifically, this article 1) discusses the basic principles of design (randomization, replication, and blocking) as they pertain to microarrays, and 2) provides some general guidelines for statisticians designing microarray studies. |
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Keywords: | Block design Composite sampling Experimental design Gene expression Microarray Replication |
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