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Development of a soft‐sensor based on multi‐wavelength fluorescence spectroscopy and a dynamic metabolic model for monitoring mammalian cell cultures |
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| Authors: | Kaveh Ohadi Raymond L. Legge Hector M. Budman |
| Affiliation: | 1. Department of Chemical Engineering, University of Waterloo, Waterloo, Ontario;2. +1‐519‐888‐4567 ext. 3012+1 519 8884347 |
| Abstract: | |
| Keywords: | Extended Kalman Filter (EKF) bioprocess monitoring multi‐wavelength fluorescence spectroscopy partial least squares (PLS) dynamic metabolic flux model soft sensor |