| 弱激光通过激活Src增强巨噬细胞吞噬功能 |
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| 引用本文： | 周非凡,陆翠霞,邢达.弱激光通过激活Src增强巨噬细胞吞噬功能[J].激光生物学报,2011,20(4):444-447. |
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| 作者姓名： | 周非凡 陆翠霞 邢达 |
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| 作者单位： | 华南师范大学生物光子学研究院激光生命科学研究所、暨激光生命科学教育部重点实验室,广东广州,510631 |
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| 基金项目： | 科技部国家重点基础研究973计划项目(2011CB910402;2010CB732602); 教育部“长江学者与创新团队计划”创新团队项目(IRT0829); 国家自然科学基金项目(30870676;30870658)资助 |
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| 摘 要： | 巨噬细胞对病原菌的吞噬以及随后的降解在机体免疫防御中起重要作用.近年来,对增强巨噬细胞吞噬能力的研究越来越被重视.弱激光具有独特的生物组织学作用特征,从而调节机体多种功能.本文重点探讨了He-Ne激光(632.8 nm)照射对巨噬细胞吞噬功能的影响及分子信号调控机理.实验结果表明,弱激光能够通过激活巨噬细胞内Sre激酶...
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| 关 键 词： | 弱激光 巨噬细胞 吞噬 Src |
Low-power Laser Irradiation Enhance Macrophage Phagocytic Capacity through Src Activation |
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| ZHOU Feifan,LU Cuixia,XING Da.Low-power Laser Irradiation Enhance Macrophage Phagocytic Capacity through Src Activation[J].ACTA Laser Biology Sinica,2011,20(4):444-447. |
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| Authors: | ZHOU Feifan LU Cuixia XING Da |
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| Institution: | ZHOU Feifan,LU Cuixia,XING Da~* (MOE Key Laboratory of Life Science & Institute of Laser Life Science,College of Biophotonics,South China Normal University,Guangzhou 510631,Guangdong,China) |
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| Abstract: | Phagocytosis and subsequent degradation of pathogens by macrophages play a pivotal role in host innate immunity in mammals.Laser irradiation has been found to produce photobiological effects with evidence of inteiference with organic functions.In this studv,we focused our attention on the effects of He-Ne laser on the phagocytic activity of macrophages, the regulation mechanism of phagocytosis was also discussed.Our results indicated that Low-power laser irradiation can enhance the phagocytosis of macrophag... |
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| Keywords: | low-power laser irradiation macrophage phagocytosis Src |
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