PDZ-peptide complexes: as exciting as ever |
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| Authors: | Trave Gilles |
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| Institution: | UMR 7242 CNRS-Université de Strasbourg, Ecole Superieure de Biotechnologie de Strasbourg, Boulevard Sébastien Brant, BP 10413, 67412 Illkirch, France. trave@unistra.fr |
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| Abstract: | In this issue, Babault et?al. present a structural analysis of the PDZ domain of the PTPN4 phosphatase, free and bound to target peptides. This allows them to enhance the cell-killing properties of a pro-apoptotic peptide dramatically. |
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