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A rapid quantitative method for the determination of thebaine in Papaver bracteatum
Authors:David Lavie  July Rotman  Arieh Levy  Dan Palevitch
Affiliation:1. Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot, Israel;2. Division of Medicinal Plant, Agricultural Research Organization, The Volcani Center, Bet Dagan, Israel
Abstract:A rapid method enabling a quantitative analysis of thebaine in capsules and latex of Papaver bracteatum has been devised, based on a TLC technique. This method was compared to the commonly used GLC procedure, and highly significant correlation coefficient (r = 0.90) and linear regression were found between the two methods. Values for concentrations to the nearest ±0.25% of the standard spots can be reached by this simple and rapid thebaine determination.
Keywords:Papaveraceae  TLC  thebaine analysis  alkaloid.
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