Eki2 is upregulated specifically in the testis during mouse sex determination |
| |
| Authors: | Hurley Tanya M McClive Peter J Sarraj Mai A Sinclair Andrew H |
| |
| Affiliation: | Murdoch Children's Research Institute, Centre for Hormone Research, Department of Paediatrics, University of Melbourne, Royal Children's Hospital, Melbourne, Vic 3052, Australia. |
| |
| Abstract: | ![]()
We have identified a gene with gonad restricted expression throughout mouse development, which is orthologous to human EKI2 (ethanolamine kinase 2). Our studies showed that mouse Eki2 expression became upregulated in the male gonad during the period of sex determination. Expression was restricted to the Sertoli cells of the developing testis. Eki2 has sequence similarity to ethanolamine (73%) and choline kinases (54%). |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
