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Bioconversion of substituted naphthalenes to the corresponding salicylic acids
Authors:G Bestetti  P Di Gennaro  E Galli  B Leoni  F Pelizzoni  G Sello  D Bianchi
Institution:(1) Dipartimento di Genetica e di Biologia dei Microorganismi, Università degli Studi di Milano, Via Celoria 26, 20133 Milano, Italy;(2) Dipartimento di Chimica Organica e Industriale, Centro di Studio per le sostanze organiche naturali del CNR, Università degli Studi di Milano, Via Venezian 21, 20133 Milano, Italy;(3) Istituto Guido Donegani, Via Fauser 4, 28100 Novara, Italy
Abstract:The Pseudomonas fluorescens N3 was isolated from soil for its ability to utilize naphthalene as a carbon source. The strain transforms 2,3-dimethyl-, 2-methoxy-, 1- and 2-ethylnaphthalenes to the corresponding salicylic acids competitively with chemical synthesis. The identification of 2-hydroxy-2-carboxy-7-ethylchromane by biotransformation of 2-ethylnaphthalene, contributes to elucidating the steps involved in the catabolic pathways of naphthalenes to salicylaldehydes. Correspondence to: F. Pelizzoni
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