Attenuation by catecholamine antagonists of the hypothermia that follows cerebral infarction in gerbils. |
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| Authors: | M A Moskowitz E Meyer R J Wurtman M H Lavyne T Zervas |
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| Affiliation: | 1. Laboratory of Neuroendocrine Regulation Department of Nutrition and Food Science Massachusetts Institute of Technology Cambridge, Massachusetts 02139, USA;2. Department of Neurosurgery Harvard Medical School Boston, Massachusetts 02115, USA |
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| Abstract: | The hypothermia that follows induction of cerebral infraction in gerbils can be attenuated by drugs which reduce the interactions between endogenous brain catecholamines and postsynaptic receptors. This observation is compatible with the hypothesis that stroke-induced hypothermia is mediated, in part, by the release of catecholamines from ischemic neurons. |
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