Inhibitory effects of echinoisoflavanone and sophoraisoflavanone D in Sophora chrysophylla SEEM on lipid peroxidation of mice brain homogenate by interaction of ferrous ion and hydrogen peroxide, in vitro |
| |
| Authors: | Shizuo Toda Yoshiaki Shirataki |
| |
| Institution: | (1) Department of Pharmaceutical Science, Kansai College of Oriental Medicine, 2-11-1 Wakaba, Kumatori, Sen-nan, 590-0482 Osaka, Japan;(2) Faculty of Pharmaceutical Science, Josai University, 1-1, Keyakidai Sakado, 350-0295 Saitama, Japan |
| |
| Abstract: | We present the results of an in vitro investigation of the inhibitory effects of echinoisoflavanone and sophoraisoflavanone
D isolated from Sophora chrysophylla SEEM on lipid peroxidation of mice brain homogenate by interaction of ferrous ion and hydrogen peroxide, in vitro. They inhibited
lipid peroxidation. The order of inhibitory effects of these isoflavanones and mannitol as a hydroxy radical scavenger was
echinoisoflavanone > mannitol > sophoraisoflavanone D. The results suggest that some isoflavanones may be of use in cases
where oxidative stress is present. |
| |
| Keywords: | Echinoisoflavanone ferrous ion hydrogen peroxide sophoraisoflavanone D Sophora chrysophylla SEEM |
| 本文献已被 SpringerLink 等数据库收录！ |
|
