| SELDI-TOF-MS技术在实验诊断中的应用 |
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| 引用本文： | 姜伟,王开正.SELDI-TOF-MS技术在实验诊断中的应用[J].生物技术通讯,2007,18(1):169-173. |
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| 作者姓名： | 姜伟 王开正 |
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| 作者单位： | 泸州医学院,附属医院检验科,四川,泸州,646000 |
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| 摘 要： | 表面增强激光解析电离飞行时间质谱(surface-enhanced laserdesorption/inionation-time of flight-mass spectra,SELDI-TOF-MS)为蛋白质组学研究提供了最为有效的技术平台。它将芯片技术和飞行时间质谱技术相结合,整合样品分离、纯化及检测分析为一体,实现了快速、高效、高通量检测,是在分子水平上诊断疾病的非常重要的工具。
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| 关 键 词： | 蛋白质组学 检验医学 |
| 文章编号： | 1009-0002（2007）01-0169-05 |
| 修稿时间： | 2006-04-04 |
Application of SELDI-TOF-MS in Laboratory Diagnosis |
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| JIANG Wei,WANG Kai-zheng.Application of SELDI-TOF-MS in Laboratory Diagnosis[J].Letters in Biotechnology,2007,18(1):169-173. |
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| Authors: | JIANG Wei WANG Kai-zheng |
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| Institution: | Department of Laboratory Medcine, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, China |
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| Abstract: | The technique of surface-enhanced laser desorption/inionation-time of flight-mass spectra(SELDI-TOF-MS) provides the most effective platform for research of proteomics. SELDI-TOF-MS, which combine the technologies of proteinchip with time of flight-mass spectra and integrate separation, purification, analysis of sample and realize rapid, high performance and high throughput detection, is an extremely important tool for diagnosis of disease at the molecular level. |
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| Keywords: | SELDI-TOF-MS |
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