The lambda and P22 phage repressors |
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| Authors: | R T Sauer H C Nelson K Hehir M H Hecht F S Gimble J DeAnda A R Poteete |
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| Affiliation: | Department of Biology, Massachusetts Institute of Technology, Cambridge 02139. |
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| Abstract: | The lambda cI repressor and the P22 c2 repressor contain two structural domains. In both proteins, the N-terminal domains mediate operator recognition and positive control of transcription, and the C-terminal domains mediate subunit oligomerization and recognition of the recA protein. In some cases, structural, biochemical, and genetic studies implicate particular repressor side chains in these processes. |
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