(1) Department of Biochemistry, Inha University College of Medicine, Incheon, 400-712, Korea;(2) Intellectual Biointerface Engineering Center, Seoul National University College of Dentistry, Seoul, 110-768, Korea
Abstract:
Recombinant human tenascin peptide (hTNCIII3) that includes the Arg-Gly-Asp (RGD) cell recognition site was expressed in Escherichia coli using a prokaryotic expression system. Addition of recombinant hTNCIII3 peptide enhanced cell adhesion and survival of human chondrocytes by about 3-fold in each case.