Bone Marrow Depletion as a Coincidental Finding to Hypothermia in Macaca mulatta |
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Authors: | Stanley P Liebenberg |
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Institution: | Veterinary Medicine and Laboratory Resources Support Division, US Army Biomedical Laboratory, Aberdeen Proving Ground, MD, 21010 USA |
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Abstract: | Three of 16 juvenile rhesus monkeys (Macaca mulatta) and 1 rhesus of 79 adult rhesus and cynomolgus monkeys (Macaca fascicularis) were found comatose in a state of profound hypothermia after a heating failure occurred in the room in which they were housed. One juvenile monkey died shortly thereafter. The three other monkeys were revived with gradual warming and supportive therapy but later experienced separate acute clinical crises manifesting shock and died at 19, 31, and 51 days after the initial episode. Histopathologic findings of severe bone marrow depletion were observed in each of the three monkeys that died after the initial episode. |
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Keywords: | Bone marrow depletion Hypothermia Macaca mulatta |
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