Insulin clearance during hypoglycemia in patients with insulin-dependent diabetes mellitus. |
| |
| Authors: | M Kollind E Moberg D Liu P E Lins U Adamson |
| |
| Institution: | Department of Internal Medicine, Danderyd Hospital, Stockholm, Sweden. |
| |
| Abstract: | Eight male patients with insulin-dependent diabetes mellitus (IDDM) without residual beta-cell function were studied on two occasions in random order. In one experiment hypoglycemia was induced by a constant rate iv infusion of insulin (0.034 U/kg/h) during 150 minutes. At the other occasion an identical infusion of insulin was given, but this time euglycemia was maintained by a variable iv infusion of glucose. Plasma levels of free insulin were almost identical during the two experiments indicating that insulin clearance is not influenced by hypoglycemia in patients with IDDM. |
| |
| Keywords: | |
|
|
