Synthesis of alkyl and aryl esters of N-protected beta-homoamino acids from N-protected alpha-aminodiazoketones |
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| Authors: | Vasanthakumar G R Gopi H N Suresh Babu V V |
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| Affiliation: | Department of Studies in Chemistry, Central College Campus, Dr B R Ambedkar Veedhi, Bangalore University, Bangalore 560 001, India. |
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| Abstract: | ![]()
A simple and concomitant esterification method for the synthesis of methyl, ethyl, t-butyl, benzyl, and 9-fluorenylmethyl esters of Fmoc-/Boc-/Z-beta-homoamino acids employing Fmoc-/Boc-/Z-alpha-aminodiazoketones by Wolff rearrangement is described. The method offers good yield with purity. |
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