Influence of estradiol on the capacity to produce antibodies during experimental amebiasis of the female golden hamster]

During experimental tissular amibiasis, the level of circulating antibodies, as detected by indirect immunofluorescence, is lower in female castrated golden hamsters who have been implanted with a pellet of oestradiol than in castrated control animals. Antibodies are first detected in the serum twenty four hours after infestation and their level becomes maximal near the fourteenth day.