Diorganotin dihalide complexes of 2,2'-biimidazole. A preliminary study of their inhibitory effects on cell division |
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| Authors: | A Sánchez González J S Casas J Sordo U Russo M I Lareo B J Regueiro |
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| Institution: | Departamento de Química Inorgánica, Universidad de Santiago de Compostela, Spain. |
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| Abstract: | We report the synthesis of new complexes with the general formula (R2SnX2)y.H2BiIm, where y = 1 or 2; R = Me, Et, Bun; X = Cl or Br (for R = Et) and H2BiIm = 2,2'-Biimidazole. The complexes have been characterized by elemental analysis and M?ssbauer, infra-red and 1H n.m.r. spectroscopy and tested (like the ligand, Me2SnCl2 and Et2SnCl2) against P388D1 leukemic cells. |
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