Chromosome studies in 952 infertile males with a sperm count below 10 million/ml |
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Authors: | G Bourrouillou N Dastugue P Colomies |
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Institution: | (1) Service de Génétique Médicale, Centre Régional de Transfusion Sanguine, CHU Purpan, F-31052 Toulouse Cédex, France |
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Abstract: | Summary A major chromosomal abnormality was observed in 10.3% of subfertile men in this study. This result is similar to a previous survey using the same criteria for selection of probands. The high frequency of chromosomal abnormalities emphasizes the importance of cytogenetic examination in subfertile men. The detection of such an abnormality should be followed by chromosome analysis in the patient's family. Prenatal diagnosis is indicated if a subfertile man with an abnormal karyotype fathers a child. |
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