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Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives
Authors:Bozda?-Dündar Oya  Ozgen Ozen  Mente?e Arzu  Altanlar Nurten  Atli Onur  Kendi Engin  Ertan Rahmiye
Institution:1. Ankara University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 06100 Tando?an, Ankara, Turkey;2. Hacettepe University, Department of Physics Engineering, 06800 Beytepe, Ankara, Turkey;3. Ankara University, Faculty of Pharmacy, Department of Microbiology, Tando?an, Ankara, Turkey
Abstract:In this study, a series of thiazolyl thiazolidine-2,4-dione derivatives (Va-f and VIa-f) were synthesized and evaluated for their antibacterial and antifungal activities against Staphylococcus aureus (ATCC 25923), methicillin resistant S. aureus (MRSA ATCC 43300), methicillin resistant S. aureus (MRSA isolate), and Escherichia coli (ATCC 23556) and C. albicans (ATCC10145). All the compounds were found active against used microorganisms.
Keywords:
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