| 软珊瑚Nephthea sp.中新生物碱分离与结构鉴定(英文) |
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| 引用本文： | 王长军,徐石海,廖小建,林慧. 软珊瑚Nephthea sp.中新生物碱分离与结构鉴定(英文)[J]. 天然产物研究与开发, 2010, 22(1) |
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| 作者姓名： | 王长军 徐石海 廖小建 林慧 |
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| 作者单位： | 暨南大学化学系,广州,510632 |
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| 基金项目： | supported by the National High Technology Development Project(863 Project,No.2006AA09Z408); National Natural Science Fund(No.20772048) |
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| 摘 要： | 一个新的化合物Nephoxaloid(1)具有独特的三环骨架结构和一个已知的化合物蕨藻素Caulerpin(2)从中国国西沙群岛的软珊瑚Nephthea sp.中分离得到。通过NMR和MS对它们的平面结构进行分析,化合物(1)和(2)对少数癌细胞株具有细胞毒性作用也有报道。
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| 关 键 词： | 软珊瑚 生物碱 结构鉴定 |
A New Alkaloid from the Soft Coral Nephthea sp. |
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| WANG Chang-jun,XU Shi-hai,LIAO Xiao-jian,LIN Hui. A New Alkaloid from the Soft Coral Nephthea sp.[J]. Natural Product Research and Development, 2010, 22(1) |
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| Authors: | WANG Chang-jun XU Shi-hai LIAO Xiao-jian LIN Hui |
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| Affiliation: | WANG Chang-jun,XU Shi-hai,LIAO Xiao-jian,LIN Hui Department of Chemistry,Jinan University,Guangzhou 510632,China |
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| Abstract: | Nephoxaloid(1),possessing an unprecedented tricyclo-skeleton,together with the known alkaloid Caulerpin(2)have been isolated from the soft coral Nephthea sp.Collected in the Xisha island of China.Their planar structures were established by NMR and MS spectroscopic analysis.The cytotoxic activity of them toward a limited panel of cancer cell lines is also reported. |
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| Keywords: | soft coral alkaloid nephoxaloid cytotoxic activities |
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