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益生芽孢杆菌对动物免疫功能影响研究进展
引用本文:谷笑笑,王振华,潘康成.益生芽孢杆菌对动物免疫功能影响研究进展[J].微生物学通报,2016,43(9):2079-2085.
作者姓名:谷笑笑  王振华  潘康成
作者单位:1. 四川农业大学动物医学院 动物微生态研究中心 四川 成都 611130,2. 成都农业科技职业学院 四川 成都 611130,1. 四川农业大学动物医学院 动物微生态研究中心 四川 成都 611130
基金项目:国家自然科学基金项目(No. 31472130);四川省高等学校科技创新团队资助项目(No. KM406183.1)
摘    要:益生芽孢杆菌是一种新型的微生态制剂,其抗性好,具有调节动物肠道微生态平衡、促进机体消化与吸收、增强动物免疫功能、提高动物生产性能等益生效应,在动物养殖业中得到了广泛的应用。本文主要综述了益生芽孢杆菌对动物免疫器官、特异性免疫、非特异性免疫和红细胞免疫等免疫功能的影响,免疫调节和产生抗菌物质两方面的作用机理,以及影响免疫效果的因素,提出有待研究的方向和解决的方法,为益生芽孢杆菌的应用提供理论参考。

关 键 词:益生芽孢杆菌,免疫功能

Advances in applying probiotic Bacillus to animal immune modulation
GU Xiao-Xiao,WANG Zhen-Hua and PAN Kang-Cheng.Advances in applying probiotic Bacillus to animal immune modulation[J].Microbiology,2016,43(9):2079-2085.
Authors:GU Xiao-Xiao  WANG Zhen-Hua and PAN Kang-Cheng
Institution:1. Animal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan 611130, China,2. Chengdu Vocational College of Agricultural Science and Technology, Chengdu, Sichuan 611130, China and 1. Animal Microecology Institute, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, Sichuan 611130, China
Abstract:Bacillus as novel micro-ecological agent has been widely used in livestock and poultry industry due to its robust resistance to extreme environment and the advantages of some probiotic effects, such as regulating intestinal microbial balance, promoting the digestion and absorption, enhancing animal immune function, and improving animal production. Our review focuses on effects of probiotic Bacillus on animal immune function covering animal immune organs, specific immune function, non-specific immune function and erythrocyte immune function. In addition, it shows the mechanism of probiotic Bacillus on animal immune function including immune regulation and synthesis of antimicrobial compounds. Furthermore, future research needs are proposed.
Keywords:Probiotic Bacillus  Immune modulation
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