A linkage group with FRA16B (the fragile site at 16q22.1) |
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Authors: | J. C. Mulley V. J. Hyland A. Fratini L. J. Bates A. K. Gedeon G. R. Sutherland |
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Affiliation: | (1) Cytogenetics Unit, Department of Histopathology, Adelaide Children's Hospital, 5006 North Adelaide, S.A., Australia |
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Abstract: | Summary Polymorphic DNA markers located in bands 16q13, 16q21 and 16q22 were examined for recombination with FRA16B, the fragile site at 16q22.100. A tight linkage cluster D16S10-FRA16B-D16S4-HP was established. There were no recombinants between D16S10 and D16S4, which flank FRA16B. The markers D16S10 and D16S4 are in close proximity on the genetic map and delineate a small chromosomal segment, which contains the distamycin A-inducible fragile site. |
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