Use of a bioassay to evaluate the toxicity of beauvericin to bacteria |
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Authors: | Castlebury L.A. Sutherland J.B. Tanner L.A. Henderson A.L. Cerniglia C.E. |
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Affiliation: | (1) Systematic Botany and Mycology Laboratory, U.S. Department of Agriculture, Agricultural Research Service, Beltsville, MD, 20705, U.S.A;(2) Division of Microbiology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, Arkansas, 72079, U.S.A |
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Abstract: | An agar diffusion bioassay was used to compare the sensitivities of bacteria to the mycotoxin beauvericin. Bacillus pumilus LACB101 was inhibited by filter-paper disks containing 0.1 g of beauvericin; B. cereus, B. mycoides, B. sphaericus, Paenibacillus alvei, P. azotofixans, P. macquariensis, and P. pulvifaciens by 1 g; and P. validus by 25 g. The anaerobes Eubacterium biforme, Peptostreptococcus anaerobius, P. productus, Bifidobacterium adolescentis, and Clostridium perfringens were also inhibited by beauvericin. |
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Keywords: | Anaerobes bacteria beauvericin bioassay mycotoxins |
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