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Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor
Authors:Monique Gangloff,Christopher   J. Arnot,Miranda Lewis,Nicholas   J. Gay
Affiliation:1. Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK
Abstract:
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  • Highlights? The N-terminal cap of Toll adopts a new fold ? It resembles a duplicated beta hairpin structure with three disulphide bonds ? Toll LRRNT cap is not critical for Spätzle binding ? The first 13 LRRs are sufficient for Spätzle binding
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