1. Department of Medicinal Chemistry, University of Washington, Seattle, WA 98195, USA;2. Department of Bioengineering and Therapeutic Sciences, Department of Pharmaceutical Chemistry, and California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA
Abstract:
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Highlights? MW determined from zero angle scattering is accurate for glycoproteins ? All-atom modeling with SAXS data can identify structural features of glycans ? SAXS ab initio reconstructions provide little structural information for glycans